R/Stats Office Hours
R/Stats Office Hours
CCB hosts weekly help sessions for analyzing and visualizing data in R, as well as providing statistical advice on research questions. HMS students, postdocs, research staff, and faculty can book […]
CCB is happy to provide computational and data science resources for HMS graduate students, postdoctoral fellows, research staff, and faculty across all departments of the HMS quadrangle.
Please email us for additional information on project collaboration, tool/technology development, educational resources, or any general inquiries.
Seminar Topics: Subject areas include single-cell, spatial, and multi-omics approaches, image analysis, knowledge representation and ontologies, and computational aspects underlying the analysis of large and hard-to-manage volumes of biomedical data. CCB invites HMS-affiliated researchers and external speakers to present their work on these topics with the goal of fostering exchange and stimulating discussions between researchers, experimentalists, computational biologists, data scientists, and software developers. We welcome suggestions for future speakers! Please submit these requests via email to Ludwig Geistlinger for review.
Attendees: Graduate and medical students, postdocs, research staff and faculty interested in getting up to speed with current breakthrough innovations for obtaining and analyzing biomedical data. If interested in staying up-to-date on upcoming seminars, submit a request to be added to the seminar mailing list.
Past CCB Seminars: Descriptions and recordings of select past seminars can be found here.
Speaker: Rong Ma, HSPH Professor
When: Monday, May 13, 3:00 PM ET
Topic: Principled and interpretable alignability testing and integration of single-cell data
Hybrid: Countway L1-032, Click here
Abstract: Aligning and integrating different datasets is a key challenge in single-cell research. However, existing methods suffer from several fundamental and under-appreciated limitations. First, we do not have a rigorous statistical test for determining whether two single-cell datasets should even be integrated. Moreover, popular methods substantially distort the data during alignment, making the downstream analysis subject to bias and difficult to interpret. We address both challenges with a unified spectral manifold alignment and inference (SMAI) framework. SMAI is a flexible and interpretable method for aligning datasets with the same type of features, equipped with an alignability test justified by statistical theory. It preserves within-data structures and improves downstream analyses, such as identification of differentially expressed genes and imputation of spatial transcriptomics
Bio:Rong Ma is an Assistant Professor of Biostatistics at Harvard T.H. Chan School of Public Health. He received his PhD in biostatistics from the University of Pennsylvania and was a postdoctoral scholar in statistics at Stanford University. His current research focuses on statistical inference for large random matrices, spectral methods, manifold learning, and applications in biomedical sciences, especially in single-cell integrative genomics and multiomics. He was a recipient of the 2022 Lawrence D. Brown Ph.D. Student Award from the Institute of Mathematical Statistics.
Speaker: Rong Ma, HSPH Professor
When: Monday, May 13, 3:00 PM ET
Topic: Principled and interpretable alignability testing and integration of single-cell data
Hybrid: Countway L1-032, Click here
Abstract: Aligning and integrating different datasets is a key challenge in single-cell research. However, existing methods suffer from several fundamental and under-appreciated limitations. First, we do not have a rigorous statistical test for determining whether two single-cell datasets should even be integrated. Moreover, popular methods substantially distort the data during alignment, making the downstream analysis subject to bias and difficult to interpret. We address both challenges with a unified spectral manifold alignment and inference (SMAI) framework. SMAI is a flexible and interpretable method for aligning datasets with the same type of features, equipped with an alignability test justified by statistical theory. It preserves within-data structures and improves downstream analyses, such as identification of differentially expressed genes and imputation of spatial transcriptomics
Bio:Rong Ma is an Assistant Professor of Biostatistics at Harvard T.H. Chan School of Public Health. He received his PhD in biostatistics from the University of Pennsylvania and was a postdoctoral scholar in statistics at Stanford University. His current research focuses on statistical inference for large random matrices, spectral methods, manifold learning, and applications in biomedical sciences, especially in single-cell integrative genomics and multiomics. He was a recipient of the 2022 Lawrence D. Brown Ph.D. Student Award from the Institute of Mathematical Statistics.
CCB hosts weekly help sessions for analyzing and visualizing data in R, as well as providing statistical advice on research questions. HMS students, postdocs, research staff, and faculty can book […]
CCB hosts weekly help sessions for analyzing and visualizing data in R, as well as providing statistical advice on research questions. HMS students, postdocs, research staff, and faculty can book […]
Join us virtually to learn about Cellenics, a user-friendly web application for exploring your single-cell RNAseq data. Designed with wet-lab biologists in mind, Cellenics was developed by Dr. Peter Kharchenko (HMS, DBMI) […]
Join us virtually to learn about Cellenics, a user-friendly web application for exploring your single-cell RNAseq data. Designed with wet-lab biologists in mind, Cellenics was developed by Dr. Peter Kharchenko (HMS, DBMI) […]
Date: Monday, 05/13/2024 Time: 3:00 pm- 5:00 pm EST Location: Hybrid (Countway L1-024) Register Here This beginner workshop is an introduction to the inference and analysis of gene regulatory […]
Speaker: Rong Ma, HSPH Professor When: Monday, May 13, 3:00 PM ET Topic: Principled and interpretable alignability testing and integration of single-cell data Hybrid: Countway L1-032 or Zoom Dr. Ma will be staying […]
About: The Image Analysis Collaboratory and the Core for Imaging Technology & Education (formerly the Nikon Imaging Center) are running a workshop over two afternoons: Introduction to image analysis using […]
About: The Image Analysis Collaboratory and the Core for Imaging Technology & Education (formerly the Nikon Imaging Center) are running a workshop over two afternoons: Introduction to image analysis using […]
CCB hosts weekly help sessions for analyzing and visualizing data in R, as well as providing statistical advice on research questions. HMS students, postdocs, research staff, and faculty can book […]
About: QuPath is a user-friendly, cross-platform, open-source software designed for digital pathology and whole slide image analysis. Since its initial release in 2017, it has become an essential tool for […]
About: QuPath is a user-friendly, cross-platform, open-source software designed for digital pathology and whole slide image analysis. Since its initial release in 2017, it has become an essential tool for […]
CCB hosts weekly help sessions for analyzing and visualizing data in R, as well as providing statistical advice on research questions. HMS students, postdocs, research staff, and faculty can book […]
CCB hosts weekly help sessions for analyzing and visualizing data in R, as well as providing statistical advice on research questions. HMS students, postdocs, research staff, and faculty can book a specific time slot by emailing Andrew Ghazi or are welcome to drop-in throughout the 2 hour session to ask for help using R or […]