Speaker: Ricard Argelaguet, Ph.D.

Topic: Principles and challenges in single-cell data integration

When: Monday, November 6, 2023, 3 PM- 4 PM ET

Abstract:The development of single-cell multimodal assays provides a powerful tool for investigating multiple dimensions of cellular heterogeneity. A key challenge in the analysis of single-cell multimodal data is to devise appropriate strategies for integrating data across different modalities. In the first part of the talk I will present an overview of principles and challenges in single-cell data integration. In the second part I will present a study on how to integrate gene expression and chromatin accessibility to predict transcription factor binding sites, infer gene regulatory networks and generate in silico predictions of transcription factor perturbations.

Virtual: Zoom link