Speaker: Ayush Noori

Topic: Contextual deep learning on knowledge graphs for drug repurposing and precision medicine in neurological disorders

When: Monday, October 30, 2023, 3 PM- 4 PM ET

Where: Countway Library 5th floor, Lahey Room 518/ Zoom

Anstract :Neurological disorders are the leading global cause of disability, yet new drugs are often developed by focusing on only a small handful of disease targets. Traditional therapeutics discovery strategies have been hampered by disease complexity and heterogeneity. To address these challenges, we developed CIPHER, a multimodal graph-language approach for contextually informed precision healthcare in neurological disease. We seek to understand network disruption in neurological disorders, predict drug repurposing opportunities, and address disease heterogeneity by enabling personalized decision making for individual patients. CIPHER successfully predicts drug-disease indications and was validated on recent FDA repurposing approvals.

Virtual: Zoom link