Speaker: Charles Reilly, Ph.D.

Topic: Broad-spectrum Antiviral and Biostasis Therapeutics Enabled by Computational Design and Discovery

When: Monday, October 16, 2023, 10 AM- 11 AM ET

Where: Harvard Medical School’s Countway Library, Lahey room(Harvard ID required)

Abstract: Broad-spectrum Antiviral and Biostasis Therapeutics are key programs under the Wyss Institute’s Computational Design and Discovery initiative. This initiative merges experimental data with in silico modeling, using predictive analytics, machine learning, and multiscale simulations. The Antiviral program harnesses simulation and machine learning to develop antiviral therapeutics for pandemic preparedness by targeting conserved viral protein changes essential for host cell entry. The Biostasis program focuses on discovering molecules to slow all biological activity, prolonging the window for emergency medical intervention after severe injuries or infections. These efforts extend beyond medicine and are being developed to minimize cold storage requirements and reduce food spoilage. This program also reveals innovative therapeutic strategies and insights into bioactive phytonutrients.

Virtual: Zoom link