OpenGWAS Ontology Mapping

Project Status

Ongoing

Project Deliverable

To improve the reusability and to facilitate the meta-analysis of GWAS data for HMS researchers.

Collaborator Name

OpenGWAS

HMS Department

Center for Computational Biomedicine

Project Description

OpenGWAS is a database containing billions of genetic associations derived from Genome-Wide Association Studies (GWAS) aggregated from dozens of sources, such as FinnGen and the UK Biobank. The phenotypes are represented differently in these sources, so our work with OpenGWAS involves the standardization of phenotypes with ontology descriptions to facilitate data integration. Our goal is to improve the reusability and to facilitate the meta-analysis of GWAS data.